There are more than 100 compounds present in the cannabis plant, according on current knowledge. Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the two most plentiful and well-known chemicals. Each of these cannabinoids has its own set of characteristics and can have various effects on the body.
The most obvious difference is that THC makes you feel good, whereas CBD does not. Furthermore, while CBD may be obtained from the cannabis plant, there are restrictions on where it can come from owing to legal issues.
Hemp & Cannabis – What’s the Difference & What Can They Do for The Body?
Cannabis and hemp are two different varieties of the cannabis plant, with only a legal difference between them. Hemp has less than .3 percent THC content, whereas cannabis has more than that.
Hemp and cannabis utilize the same endocannabinoid system (ECS) in the human body, which governs their effects. The endocannabinoid system (ECS) is a collection of receptors and endocannabinoids that influence them. These combine to have an influence on a wide range of essential activities, including pain, hunger, sleep, and more.
Cannabis also contains various cannabinoids, terpenoids, and flavonoids that are beneficial to the body. THC and CBD are by far the most prevalent of these chemicals, with a lot of study dedicated to them. But what are they, how do they function, and why are they diverse from one another?
CBD & THC – The Superstar Cannabinoids
Until fairly recently, the majority of people associated cannabis with getting high, so the interest was just on THC. Scientists have lately found CBD and other cannabinoids, suggesting that another avenue for studying the therapeutic advantages of marijuana opens up. Both THC and CBD are cannabinoids in the cannabis plant, and both are present in the crystalline resinous trichomes that cover a mature cannabis flower. Each strain, however, creates significantly different quantities of each chemical.
What is THC & How Does It Work?
THC is the most essential and popular star in the cannabis plant, and it is what makes people high. While a high-THC strain will undoubtedly change your brain, it may also have therapeutic benefits that are sometimes ignored.
When THC enters your brain, it activates neurons and causes dopamine release. THC also activates cannabinoid receptors in the brain, which have a wide range of effects. While some THC strains provide you with a burst of energy and creativity, other strains give you a relaxing effect as the high takes over your body. The effects of particularly potent cannabis strains can strike you within 10 minutes. Here are some of the most common effects of THC:
- Increase in appetite
What is CBD & How Does It Work?
Cannabidiol (CBD) is a cannabinoid that does not cause intoxication and is frequently used to treat illnesses since there is no ‘high’ associated with it. While experts are still researching how CBD works in the body, studies indicate that it interacts with the ECS. CB1 and CB2 are two of the main cannabinoid receptors found in the ECS. The CB1 receptors are mostly located in the brain and have a significant role in memory, sleep, mood, hunger, pain sensation, and other functions.
Cannabidiol (CBD) has two types of receptors: CB1 and CB2. The endocannabinoid system, which is made up of cannabinoid receptors and endocannabinoids, regulates pain, inflammation, mood, memory, appetite, pleasure, movement disorders such as Parkinson’s disease Tremors), depression. THC binds to both kinds of receptors but CBD activates them indirectly by increasing the amount of endocannabinoids in the body. CBD also inhibits natural endocannabinoid breakdown. Here are some of CBD’s most common effects:
THC – Why the High?
When it comes to the intoxicating effects of cannabis, we must focus on CB1 receptors in the brain and nervous system. THC binds strongly to CB1, whereas CBD does not. Because THC is designed like a plug – i.e., fits well into a CB1 receptor socket – it activates these receptors effectively.
The primary cannabinoid present in cannabis, THC, has been shown to bind specifically to the CB1 receptor. Furthermore, it partially mimics the ‘bliss molecule’ called anandamide, which is a naturally occurring endocannabinoid. The fact that THC resembles anandamide means that when it binds to CB1 receptors, it contributes to the euphoric sensations associated with cannabis.
However, cannabidiol (CBD) is an antagonist of CB1 receptors and therefore is not a good fit. In fact, it inhibits the CB1-activating properties of THC. CBD, in a nutshell, means that THC’s mind-altering effects are reduced. If you consume cannabis with 22% THC, for example, you may experience dizziness or euphoria. If it also contains 8% CBD, on the other hand, the psychoactive effects will be decreased, as well as anxiety.
CBD vs. THC: Chemical structure
CBD and THC have the same molecular structure: 21 carbon atoms, 30 hydrogen atoms, and two oxygen atoms. The varying effects on your body are due to a minor variation in how the atoms are positioned.
CBD and THC are chemically similar to your body’s endocannabinoids. They may bind to your cannabinoid receptors as a result of this chemical resemblance.
The impact of the interaction on neurotransmitter production in your brain is obvious. Neurotransmitters are chemical messengers that connect neurons and have functions in pain, immune function, stress, and sleep, among other things.
CBD vs. THC: Psychoactive components
CBD and THC, despite their comparable chemical structures, do not produce the same psychotropic effects. CBD is psychoactive; however, it isn’t in the same way as THC is. It doesn’t generate the euphoria associated with THC. CBD has been proven to alleviate anxiety, sadness, and seizures.
THC binds with the cannabinoid 1 (CB1) receptors in the brain, causing a high or sense of euphoria. CBD has little affinity for CB1 receptors and cannot bind to them on its own. THC must bind to CB1 receptors in order for CBD to work and can help reduce some of the unpleasant psychotropic effects of THC, such as euphoria or sedation.
CBD vs. THC: Legality
Cannabis-related legislation is changing in the United States on a regular basis. CBD, technically speaking, remains a Schedule I substance under federal law. Hemp has been removed from the Controlled Substances Act, but CBD continues to be listed as a Schedule I drug by the Drug Enforcement Administration (DEA) and the Food and Drug Administration (FDA).
However, 33 states plus the District of Columbia have decriminalized or legalized cannabis-related laws, allowing for medical marijuana with a high THC concentration. The use of THC and cannabis for recreational purposes is now legal in several jurisdictions. CBD should be able to be found in anyplace where cannabis is lawful for either personal or therapeutic use.
Before you try to purchase CBD or THC-infused items, you should learn about your state’s restrictions. You may face legal repercussions if you have cannabis-related goods in a state where they’re prohibited or don’t have a medical prescription in states where the items are legal for medical use.
CBD vs. THC: Medical benefits
Many of the medical advantages of CBD and THC are similar. They can help with a variety of ailments. CBD, on the other hand, does not produce the same euphoric effects as THC. Because to this side effect, some individuals may prefer to utilize CBD instead of THC.
The U.S. Food and Drug Administration (FDA) green-lighted Trusted Source Epidiolex, the first prescription drug containing CBD, in June 2018. It’s used to treat uncommon, difficult-to-control sorts of epilepsy. (Epidiolex is not yet authorized for any of the other conditions listed below.)
CBD is used to help with other various conditions, such as:
- psychosis or mental disorders
- inflammatory bowel disease
THC is used to help with the following:
- muscle spasticity
- low appetite
CBD vs. THC: Side effects
CBD is a relatively safe drug, even when taken in high dosages. According to StudyTrusted Source, any CBD side effects are most likely caused by interactions between CBD and any other medicines you’re taking.
THC causes temporary side effects, such as:
- increased heart rate
- coordination problems
- dry mouth
- red eyes
- slower reaction times
- memory loss
CBD’s side effects may include:
- appetite changes
- weight loss
The negative side effects listed here are due to the drug’s psychotropic qualities. Neither is fatal. Marijuana dependence, on the other hand, has been linked to long-term mental problems in certain individuals. This is especially true for teenagers who consume a lot of THC, although there isn’t enough evidence that cannabis use causes psychiatric disorders such as schizophrenia.
CBD vs. THC: Drug testing
Cannabinoids, such as THC and CBD, are stored in the body’s fat. They may be detected for days or weeks after usage on drug tests. nNot every drug test is able to detect CBD, but there are CBD-sensitive options available. Most standard drug tests look for chemicals that are linked to THC, so marijuana use might show up on a screening.
Hemp can also generate THC in addition to CBD, so even if you haven’t used it, a test may come back positive for THC. It’s crucial to remember that goods that claim to be THC-free may not be.
Why do people talk about THC content in CBD oil if THC and CBD are two different compounds?
Cannabinoids are a class of chemicals found in cannabis that interact with cannabinoid receptors. CBD and THC are two of the most well-known cannabinoids in cannabis. Both cannabis and hemp produce CBD and THC. Cannabis has a greater concentration of THC than hemp. The average amount of THC in today’s cannabis strains is approximately 12 percent. A trusted source stated, “THC.”
CBD & THC – Better Together?
When cannabinoids, flavonoids, and terpenes from a cannabis plant are combined, they appear to work far better for medical purposes than any single component alone. The entourage effect is what causes this phenomenon; together, cannabis’ components can produce unexpected benefits that no individual component can accomplish alone.
The use of cannabis to treat chronic pain is a fantastic illustration. THC alone can handle severe discomfort effectively, but CBD can help with anxiety symptoms that might accompany chronic diseases. The use of CBD for sleep is becoming increasingly popular. Depression, arthritis, anxiety disorders, and headaches have all been shown to respond well to a combination of THC, CBD, and terpenes.
Uruguay was the first country in the world to make marijuana legal for recreational use when it did so in 2014. Bill C-45 was passed in Canada. This legislation enables individuals to possess up to 30 grams of cannabis. It also permits the sale of cannabis by authorized businesses. Cannabis is prohibited at the federal level in the United States. However, it is permitted for recreational usage in certain states.
CBD derived from the cannabis plant is classified under Schedule I of the Controlled Substances Act. It is prohibited across the United States, however it may be acquired if produced from hemp with a THC level less than 0.3%.
Final Thoughts on CBD Vs. THC
CBD has grown increasingly available due to the Farm Bill’s passage. CBD products, including oils and capsules, are now available to consumers. CBD appears to help with a number of ailments in early research. CBD, in fact, may help patients with Parkinson’s disease manage their symptoms. Future studies might reveal more about CBD and how it can be used.
THC, on the other hand, may help with a variety of ailments. CBD, on the other hand, has been found to assist with a variety of health problems. THC, for example, has been linked to greater symptom relief and mitigation in one study.
According to the study, more THC correlated with greater effects while there was no apparent relationship between the amount of CBD and symptom relief. Despite THC’s possible benefits, it has a perceptible impact on perception. For some people, its psychoactive profile may be a disadvantage.
CBD and THC can, however, help with a variety of issues when used together, including multiple sclerosis. CBD’s ability to counteract the psychoactive effects of THC has been suggested as one explanation for the effectiveness of whole-plant cannabis.
Both cannabidiol (CBD) and tetrahydrocannabinol (THC) have medical applications. They’re also both considered safe, but be wary of any possible side effects or interactions with other medications you’re taking. Before using it, talk to your doctor or a knowledgeable cannabis or CBD specialist to ensure that you understand the risks involved.
A greater understanding of how each chemical can help individuals might be better discussed and analyzed as the number of CBD and THC research expands.