Cannabis for Inflammation: How Does It Work?

None of us are alien to the uncomfortable feeling of inflammation. Whether that comes in the shape of an upset stomach, a skin rash, or a sprained ankle; inflammation is always a symptom we would rather avoid. At least if it were entirely up to us. If you’d like to buy the best Marijuana for Inflammation, use cannabis delivery to your home.

Little did we know that it actually IS up to us. Sure, in some cases like a sprained ankle or broken bone (basically anything out of your control), inflammation is inevitable. But the severity of the symptom can be managed, and the pain caused by it lowered dramatically.

We can accomplish this mainly through a balanced healthy diet, potentially heavy on foods and supplements with anti-inflammatory properties. Some of the most popular options include nuts, leafy greens, and turmeric. However, this is not an article on healthy dieting, at least not specifically.

This is an article on how cannabis can aid in controlling and suppressing inflammation. A list of the best cannabis strains to combat inflammation and help you live a healthier, happier, inflammation-free life.

What Causes Inflammation?

Inflammation is the body’s process to fight against something that harms it. For example, toxins, infections, or injuries can trigger an immune response that will cause inflammation.

Cannabis has been used to treat inflammation for centuries. Cannabinoids are very similar to the endocannabinoids produced in our endocannabinoid system.

How Is Marijuana an Effective Treatment for Inflammation?

Both CBD and THC help reduce inflammation associated with several diseases. However, beta-caryophyllene, another compound found in marijuana, affects your CB2 receptor. During a 2008 study, researchers analyzed mice with swollen paws. The researchers gave the mice oral beta-caryophyllene doses that resulted in a 70 percent reduction in inflammation. Mice that didn’t have CB2 receptors didn’t show any improvement.

Both CBD and THC not only work to treat and prevent inflammation, but they also demonstrate efficacy in reducing both the production and release of pro-inflammatory cytokines. They also cut LPS-induced STAT 1 transcription factor activation which contributes to certain inflammatory processes. Since researchers find that CBD is most effective in tackling inflammation, CBD-rich marijuana strains can be helpful for individuals with extreme inflammation.

What Symptoms of Inflammation Can Medical Marijuana Treat?

CBD helps support the concentration of endogenous cannabinoids that provide your body with the ability to ward off disease and self-heal.

Endocannabinoids help to control:

  • Muscle tone
  • Pain
  • Appetite
  • Mood state
  • Inflammation

There are over 100 different cannabinoids in marijuana, giving it the capacity for numbness and analgesia through neuromodulation in descending and ascending pain pathways, anti-inflammatory and neuroprotective mechanisms.

How to Get Medical Marijuana for Inflammation

Not all states allow patients to receive medical marijuana for inflammation. Meet with a licensed medical marijuana doctor in your state to find out if you qualify. A doctor can answer your questions and help you get the treatment you need.

Best Methods of Marijuana Treatment to Use to Treat Inflammation

These days, cannabis makes a great alternative to prescription medication that can come with serious addictive properties and side effects. In many cases, medical cannabis for inflammation can also provide a better quality of life solution than traditional medication.

Methods of administering cannabis and inflammation treatment include:

  1. Inhalation

Vaporizers are the latest “go to” for patients looking to take the inhalation route of getting their medical marijuana.

  1. Oral

Oral ingestion of medical weed offers different pharmacokinetics than inhalation. With the oral route, titration of doses is a bit more difficult, and the onset of action is delayed. It’s also a relatively inexpensive and convenient marijuana and inflammation treatment delivery system.

  1. Transdermal

CBD and THC cannabinoids are alcohol and fat soluble. Formulations that contain cannabinoids pass from the patch to your skin and into your bloodstream.

  1. Topical

Topical applications come in lotions, oils, creams and patches. Topical applications act particularly in the area of harm. They’re long-lasting, non-psychoactive, non-invasive and easy to use.

  1. Suppositories

If you’re looking for some heavy-duty help, suppositories might be it. While an uncommon method of delivery, it can be a useful route if you’re looking for therapy “on the road.” Refrigerate the medication beforehand. This method is fast, long lasting and efficient.

  1. Sublingual

Sublingual come in tinctures and essential oils. They’re fast and easy to control your dose. They’re convenient and are the preferred method for children.

When you’re ready to start your marijuana therapy for inflammation, some factors you should consider when evaluating the medical marijuana providers include:

  • Selection of cannabis available
  • Quality of marijuana
  • Attention to customers
  • Price of weed
  • Safety and health regulations
  • Delivery and location services
  • Transparency

Best Strains of Marijuana for Inflammation


We have already written about this cannabis strain. Cannatonic is rich in CBD. To be more precise, Cannatonic is a 1:1 CBD and THC cannabis strain. This characteristic makes Cannatonic a unique strain. Cannatonic is a cannabis strain developed in Spain and it is a cross of Reina Madre and NYC Diesel. This cannabis strain is perfect for beginners as its CBD content may reduce paranoia and psychosis caused by THC.


This is another cannabis strain rich in CBD. Harlequin is also excellent for cannabis newbies. Harlequin is a Sativa-rich strain with a 5:2 CBD:THC ratio. This strain is even higher in CBD than Cannatonic but still with a “decent” level of THC. Due to its high CBD-content, Harlequin is also a strain we highly recommend for beginners. Both CBD and THC are cannabinoids that reduces pain and inflammation. CBD has been used in contact sports to reduce joint inflammation and muscle soreness.

Harlequin is an excellent cannabis strain for the treatment of arthritis. In addition, due to its high CBD content, it’s unlikely you will experience THC-derived paranoia.


Another CBD-rich cannabis strain. CBD OG is an ideal cannabis strain to reduce inflammation. CBD OG has a 2:1 CBD:THC ratio. It averages 10% CBD (5% THC). This is not a CBD to get high as its THC content is low. CBD OG is a perfect medical cannabis strain. If you are looking for a strain to reduce inflammation, then you should try CBD OG. It is an excellent strain for people with a low THC tolerance.


Another cannabis strain excellent to reduce inflammation. ACDC is another CBD rich cannabis strain. ACDC is very popular for medical uses, especially useful to treat chronic pain. Many cannabis users claim this strain is very useful in combatting nerve pain.

Tangie Sunrise

Tangie Sunrise is a strain that imbues the consumer in an uplifting and happy effect. Tangie Sunrise is quite rich is THC (16% of THC) and ideal to combat inflammation as well as stress, fatigue, and depression. Tangie Sunrise is a cross between Jack Herer and Orange Crush.

Girl Scout Cookies

This strain, also known as GSC, is quite rich in THC (19% of THC). As many strains on this list, this strain is a member of the Kush family. Girl Scout Cookies is a hybrid between OG Kush and Durban Poison. Girl Scout Cookies is very effective in the treatment of chronic inflammation.

The Gift

Also known as RG8, the Gift is a cannabis strain rich in CBD with very low THC level. This strain is ideal for cannabis consumers seeking relaxing and anti-inflammatory effects without the euphoric and psychoactive effects caused by THC. The Gift is recommended for cannabis users who seek anti-inflammatory effects without worrying about paranoia and psychosis. In addition, the Gift is recommended to treat arthritis and insomnia. 

The Anti-Inflammatory Benefits of Cannabis

The cannabis plant is home to a diverse number of components called cannabinoids; 113 identified so far and potentially growing in number as scientists and botanists carry out investigations given the growing interest around the legal cannabis industry.

As with other functional foods, some cannabinoids have been found to suppress inflammatory response and attenuate the symptoms caused by it. Symptoms that include pain, tiredness, and a feeling of uncomfortability.

The ability of cannabinoids to combat inflammation has also made cannabis a point of interest in investigation correlated to autoimmune disorders like multiple sclerosis, rheumatoid arthritis, colitis, and hepatitis where the suppression of inflammation could result in protecting the patient.

According to research from Nagarkatti (2010), “Cannabinoids may also be beneficial in certain types of cancers that are triggered by chronic inflammation”. By inhibiting inflammation, they have a direct impact on tumor growth.

What To Look For In Cannabis For Inflammation

CBD is perhaps the most popular and relevant cannabinoid when it comes to combating inflammation. Largely due to its legal status in all 50 states across the U.S. and to its non-psychoactive effects.

CBD has been used for decades as a way to inhibit inflammation and combat localized physical pain. Like THC (psychoactive component of cannabis), CBD is also found in marijuana, but larger amounts of the cannabinoid are present in the ‘hemp’ plant. Hemp is a non-psychoactive alternative to the marijuana plant that contains larger amounts of CBD.

As a cannabinoid, CBD has been granted with an array of diverse benefits. Among which we find incredible anti-inflammatory properties. Hence why most of the strains included on the list in this article tend to have a higher concentration of CBD.

Side Effects of Marijuana for Inflammation

When compared with other ways to treat inflammation and the potential side effects of traditional anti-inflammatory medications, marijuana is a safe and natural alternative with little risk. While marijuana can have various effects on the body, side effects are generally mild and go away when you aren’t using cannabis.

Some of the common side effects of marijuana include:

  • A high sensation: Marijuana can create a “high” feeling in users, particularly when using strains high in THC. Many people enjoy this feeling of euphoria, but it’s important to know and plan for the fact that this high can interfere with certain activities, such as driving and work.
  • Drowsiness: When you use marijuana to treat inflammation or other symptoms, you may notice a drowsy sensation. This sensation can interfere with many daytime activities. However, it can be an advantage at nighttime when trying to fall asleep. You can request a sativa-dominant strain for when you know you need to stay alert.
  • Increased appetite: Some patients who use medical marijuana report an increase in appetite. This can be a positive or negative side effect, depending on the person. It is often a positive side effect if the patient normally has a low appetite or needs to gain weight for medical reasons.

Inflammation can cause significant discomfort and complications. Many patients find the various potential side effects of medical marijuana worth it to help treat their inflammation. Marijuana is an affordable and natural option when compared with traditional anti-inflammatory medications and other forms of treatment.

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